Daily home fortification with iron as ferrous fumarate versus NaFeEDTA: a randomised, placebo-controlled, non-inferiority trial in Kenyan children
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منابع مشابه
Daily home fortification with iron as ferrous fumarate versus NaFeEDTA: a randomised, placebo-controlled, non-inferiority trial in Kenyan children
BACKGROUND We aimed to show the non-inferiority of home fortification with a daily dose of 3 mg iron in the form of iron as ferric sodium ethylenediaminetetraacetate (NaFeEDTA) compared with 12.5 mg iron as encapsulated ferrous fumarate in Kenyan children aged 12-36 months. In addition, we updated a recent meta-analysis to assess the efficacy of home fortification with iron-containing powders, ...
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In-home fortification of infants with micronutrient powders (MNPs) containing 12.5 mg iron may increase morbidity from infections; therefore, an efficacious low-dose iron-containing MNP might be advantageous. Effects of iron-containing MNPs on infant growth are unclear. We assessed the efficacy of a low-iron MNP on iron status and growth and monitored safety in a randomised, controlled, double-...
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Method A prospective, randomised controlled trial was performed. Primary end-point was demonstrating noninferiority of miniplegia versus intermittent 4:1 blood cardioplegia in elective aortic valve replacement. For sample size calculation, a maximum increase +15% in mean peak postoperative troponin T was considered non-inferior (Δ = +474.24 ng/L). Power was 0.9, and a < 0.05 was considered stat...
متن کاملA randomised, controlled trial of once daily and multi-dose daily gentamicin in young Kenyan infants.
AIMS To test the suitability of a simple once daily (OD) gentamicin regimen for use in young infants where routine therapeutic drug monitoring is not possible. METHODS In an open, randomised, controlled trial, infants with suspected severe sepsis admitted to a Kenyan, rural district hospital received a novel, OD gentamicin regimen or routine multi-dose (MD) regimens. RESULTS A total of 297 ...
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ژورنال
عنوان ژورنال: BMC Medicine
سال: 2017
ISSN: 1741-7015
DOI: 10.1186/s12916-017-0839-z